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Can we use this script for other site where youtube is loaded with different URL inside the browser
if yes how to change the URL of the script to work on other websites instead of youtube.

The script should in theory already work for embedded videos as long as they use the same domain as normal YouTube videos..
I usually don't see ads on YouTube videos embedded on other sites though.
Do you have an example of a website that embeds videos with ads where the script isn't working?